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When you have an anal fissure it means that your bowel got injured and there is a small tear in it that brings you that horrible pain in the ass. Sometimes you can even notice some bleeding. But don't be as stupid as I was - you are not dying! What you need in this case (and what I needed as well) is Diltiazem cream that helps the tears heal. Give it several days and it will bring your anus back n order. Believe my experience!

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Gastrointestinal: Anorexia, constipation, diarrhea, dry mouth, dysgeusia, mild elevations of SGOT, SGPT, LDH, and alkaline phosphatase (see ), nausea, thirst, vomiting, weight increase.

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However, for a subgroup of patients with fissures refractory to medical therapy who are at risk of incontinence or are reluctant to undergo the gold standard surgical treatment of lateral internal sphincterotomy (LIS), we have combined injection of botulinum with fissurectomy.

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When Diltiazem was coadministered with a high fat content breakfast, the extent of Diltiazem absorption was not affected; T max, however, occurred slightly earlier.

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While all the available options are explained to the patient with complete information about the method, cure rates, complications, and reversibility of the disease, the surgeon should analyze the optimum treatment for the particular patient in order to make a good and safe choice and then offer to the patient the result of the best of judgment of his own.

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However, narcotics can cause constipation, leading to increased bleeding, pain, suture breakdown, and loose staples.

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Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure.

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But worst of all, having a fissure is a problem that you can't really explain to colleagues or friends, even those closest to you don't really want to hear about it.

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Change From Baseline in Average of Worst Anal Pain Associated With or Following Defaecation for Week 4 (for the 7 Treatment Days Immediately Preceding the Week 4 Visit).

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RCTs comparing long-term results (12 to 84 months) of both procedures found that patients were twice as likely to require further treatment after stapled hemorrhoidopexy.

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Chronic or complicated fissure in ano: The above mentioned approaches do not prove effective in the chronic variety of fissures in ano.

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In group B, patients were also advised to apply a pea size (approximately 250-500 mg) quantity of 2% diltiazem ointment by fingertip to the anus twice daily for one week.

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